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This benefit relates to CBD’s effects on anandamide. CBD’s antipsychotic effects relate to its impact on anandamide. Ultimately, the study found that CBD boosted anandamide signaling and alleviated the psychotic symptoms of schizophrenia. There is a long history of anecdotes in chronic illness communities about people using it for pain and other symptoms.
The researchers wrote that an elevation of anandamide levels in cerebrospinal fluid inversely correlates to psychotic symptoms. Translational Psychiatry in March 2012, looked into the effect of CBD on anandamide production. A study by Pretzsch et al., published in the Neuropsychopharmacology journal in February 2019, looked at the effects of CBD on brain excitation and inhibition systems.
A study by Leweke et al. A study by Cheng et al., published in the Journal of Alzheimer’s Disease in 2014, found that long-term CBD treatment "prevents the development of social recognition memory deficits in Alzheimer’s disease transgenic mice." The researchers also wrote that CBD exerts anti-inflammatory, antioxidative, and neuroprotective properties in vitro and in vivo.

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